| Week 3 |
| October 2, 1927 |
Green Bay Packers vs. Chicago Bears |
City Stadium |
| Week 4 |
| October 9, 1927 |
Cleveland Bulldogs vs. New York Yankees |
University of Detroit Stadium |
| Week 5 |
| October 16, 1927 |
Green Bay Packers vs. Chicago Cardinals |
City Stadium |
| October 16, 1927 |
Chicago Bears vs. New York Yankees |
Wrigley Field |
| Week 7 |
| October 30, 1927 |
New York Giants vs. Pottsville Maroons |
Polo Grounds |
| Week 9 |
| November 11, 1927 |
Pottsville Maroons vs. New York Yankees |
Minersville Park |
| Week 12 |
| December 4, 1927 |
New York Giants vs. New York Yankees |
Polo Grounds |
